18世纪末，美国诞生了, 但是在列强的封锁下，经济状况举步维艰，陷入困境。
1784年，美国商船"中国皇后号"跨洋过海，战胜艰难险阻，首航中国，来到乾隆时期的广州，受到了中国政商各界的热情接待和帮助，从而开通了东西方商贸通道，同时也揭开了中美两国人民友好交往的序幕！
这部小说详尽叙述了这一过程，对中美两国人民的深厚友谊给予了高度礼赞，突出了和平与发展的时代主题，昭示了国家关系归根结底是人民之间的关系。
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