《米德尔马契》一书有两条主线。其一是理想主义少女多萝西娅的灾难性婚姻与理想的破灭，其二是青年医生利德盖特可悲的婚姻与事业的失败。作者运用对比、对称、平行和重复等手法，把这两条主线巧妙地交织在一起，把众多人物写了进去，成功地表现了"社会挫败人"这样一个幻灭主题。
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